He formed DENKI GROOVE with Pierre Taki and others in 1989.
The first solo album "DOVE LOVES DUB" was released in 1995.
It was during this time that he seriously started his career as a DJ. In 1997, with the main focus in Europe, he also began his career abroad.
In 1998, he performed in front of 1.5 million people at the Final Gathering at the world's biggest techno music festival, "Love Parade", in Berlin.
From 1999 to 2013, He headed an event called "WIRE", Japan's largest indoor rave with over 10,000 audiences, and he vigorously introduced foreign DJs and artists to Japan.
In December 2015, he was the only Japanese person to be solely in charge of the single cut "Tuitti Fruitti" remix for the new album of New Order, "Music Complete". Later in August 2016, the first original solo album in six years, "LUNATIQUE" , December 2017 “ACID TEKNO DISKO BEATz”, January 2018 “Takkyu Ishino Works 1983～2017” was released. Right now, he is actively working as a DJ, producer and remixer.